tag:blogger.com,1999:blog-63151317856885442292024-03-05T17:52:11.320-08:00Ferdi Hellweger BlogFerdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.comBlogger93125tag:blogger.com,1999:blog-6315131785688544229.post-65413467860173267442018-01-22T02:49:00.000-08:002018-01-22T02:49:35.261-08:00A new chapter in my life: TU Berlin<span style="font-family: Arial, Helvetica, sans-serif;">Dear Friends and Colleagues:</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">On 1. January 2018 I started at the Technical University of Berlin as Chair of Water Quality Engineering (Wasserreinhaltung). This web site <a href="http://www.systemsbioecology.org/">www.SystemsBioEcology.org</a> will not be updated anymore in the foreseeable future. To find out whats new with me you can visit my web site at TU Berlin: </span><a href="http://www.wrh.tu-berlin.de/" style="font-family: Arial, Helvetica, sans-serif;">http://www.wrh.tu-berlin.de</a>.<br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Sincerely,</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;">Ferdi Hellweger</span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiDvZ4EfvmsgtW0SgpXyfj-wAlowD0k3Fk7S1r5_QcUh77RbWZDO5EWt8NqbddCz8GXCxdxGtyqxTI9T8CnzJv2sfLRNOHCj3guIDNTV98jPrT4gHuXrkpRYAFGCfgvrJ4PmIHbKmhsobhu/s1600/teaser_LichthofNike_boeck.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><span style="font-family: Arial, Helvetica, sans-serif;"><img border="0" data-original-height="216" data-original-width="241" height="358" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiDvZ4EfvmsgtW0SgpXyfj-wAlowD0k3Fk7S1r5_QcUh77RbWZDO5EWt8NqbddCz8GXCxdxGtyqxTI9T8CnzJv2sfLRNOHCj3guIDNTV98jPrT4gHuXrkpRYAFGCfgvrJ4PmIHbKmhsobhu/s400/teaser_LichthofNike_boeck.jpg" width="400" /></span></a></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><span style="font-size: x-small;">Lichthof mit Nike-Statue im TU-Hauptgebäude</span></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif; font-size: x-small;">© TU Berlin/Böck</span></div>
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<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-18002384578398626762017-08-04T12:58:00.003-07:002017-08-04T12:58:37.467-07:00Congratulations and thanks to YSPs Olivia and Isabel<span style="font-family: Arial, Helvetica, sans-serif;">Congratulations and thanks to Olivia Hanna and Isabel Koran on a nice summer project investigating the water quality at the future Charles River swimming site. Olivia and Isabel are high school students that joined our research group this summer through Northeastern’s Young Scholars Program (see link below). They were supervised and worked closely with PhD student Max Rome. Olivia and Isabel went out and measured <i>E. coli</i> and cyanobacteria at a number of sites and found some very interesting spatial and temporal patterns, like hotspots of <i>E. coli</i> at certain locations. Here is a picture I took during their final presentation.</span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhzkWaOo-ZA2HSRqhJ9oJ5T6tZ4R0CwMeKB9quq8t32Bxoe7h1DwNDhiy2W9nrjA_3MOsagRwT_Z2FYXUm35yFPvj7-FMOzHPPTm545chpxCA_Zn1QWzJlWBceGT6RCzPgviqE3_Y1xP5gC/s1600/YSP2017.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><span style="font-family: Arial, Helvetica, sans-serif;"><img border="0" data-original-height="900" data-original-width="1600" height="225" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhzkWaOo-ZA2HSRqhJ9oJ5T6tZ4R0CwMeKB9quq8t32Bxoe7h1DwNDhiy2W9nrjA_3MOsagRwT_Z2FYXUm35yFPvj7-FMOzHPPTm545chpxCA_Zn1QWzJlWBceGT6RCzPgviqE3_Y1xP5gC/s400/YSP2017.jpg" width="400" /></span></a></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://stem.neu.edu/summer/ysp/">https://stem.neu.edu/summer/ysp/</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.thecharles.org/swim-park-project/">http://www.thecharles.org/swim-park-project/</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.systemsbioecology.org/">www.systemsbioecology.org</a></span><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-1378426940339849612017-07-19T01:46:00.001-07:002017-07-19T01:46:35.677-07:00Congratulations to Scott & Ryan for a successful defense<span style="font-family: Arial, Helvetica, sans-serif;">Scott Simpson and Ryan Shae successfully defended their MS theses as part of the Gordon Engineering Leadership program. Scott’s thesis -Modeling and Analysis of Forecast-Integrated Stormwater Discharge Control Systems - focused on developing automated control of stormwater infrastructure based on weather forecasts. The idea is that retention ponds release their stored water ahead of a storm to increase the storage volume and decrease runoff and damage to downstream infrastructure. Ryan’s project - Eliminating Unaccounted for Water in the Dedham-Westwood Water District - dealt with combating water loss in distribution systems. By isolating parts of a system and combining various sources of data, Ryan was able to get a better estimate of the losses and their likely cause.</span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEic1v4T58uyfil6s8b5OPQaFU4E692JZDcZi_ZEgebktzdi0Tr1VntJWOXCOhm_Gw-Rc8k39jmwLLuO3DGMuhZGkgD5wU75Znr36bYzc47OX7rLYPNOuLxi0o2mKkHgAa7MPNVXyFRRsLLI/s1600/Simpson.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="451" data-original-width="777" height="231" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEic1v4T58uyfil6s8b5OPQaFU4E692JZDcZi_ZEgebktzdi0Tr1VntJWOXCOhm_Gw-Rc8k39jmwLLuO3DGMuhZGkgD5wU75Znr36bYzc47OX7rLYPNOuLxi0o2mKkHgAa7MPNVXyFRRsLLI/s400/Simpson.jpg" width="400" /></a></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><span style="font-size: x-small;">Image from Scott Simpson thesis.</span></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.northeastern.edu/gordonleadership/">http://www.northeastern.edu/gordonleadership/</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.systemsbioecology.org/">www.systemsbioecology.org</a></span><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-56687481850207546322017-07-08T02:19:00.000-07:002017-07-08T02:19:07.827-07:00CBAD: Community Biological Ammonium Demand<span style="font-family: Arial, Helvetica, sans-serif;">I am pleased to announce our recent publication in ES&T under the leadership of Wayne Gardner from the University of Texas. In this paper we present the concept of CBAD (community biological ammonium demand) to help understand CyanoHAB ecology. (C)BAD is similar to BOD (biochemical oxygen demand), a well-known and proven concept in environmental engineering and we hope BAD will be useful for advancing understanding and managing lakes plagued by CyanoHABs.</span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhM8j6JFnUaZUttoLvMs-OsAT7BLCqko1c5IOBgeWm8jqnZ_kjOWzh9YuaNz-n8vyeZ3OI3MOnClQphU-LAq9wFaXatadlTev0uZJu7RFMlfPQGHwwVuVBYf8h8H9xgNUh7L2y4EC8EZWOk/s1600/est2017.jpeg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="562" data-original-width="971" height="231" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhM8j6JFnUaZUttoLvMs-OsAT7BLCqko1c5IOBgeWm8jqnZ_kjOWzh9YuaNz-n8vyeZ3OI3MOnClQphU-LAq9wFaXatadlTev0uZJu7RFMlfPQGHwwVuVBYf8h8H9xgNUh7L2y4EC8EZWOk/s400/est2017.jpeg" width="400" /></a></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://pubs.acs.org/doi/full/10.1021/acs.est.6b06296">http://pubs.acs.org/doi/full/10.1021/acs.est.6b06296</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.systemsbioecology.org/">www.systemsbioecology.org</a></span><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-23797958641969171562017-06-05T07:27:00.000-07:002017-06-05T07:27:12.477-07:00ASM Microbe 17 Conference Report<span style="font-family: Arial, Helvetica, sans-serif;">I am at ASM in New Orleans. Today, I will make a presentation about our work on individual-based, genome-scale modeling of microbe ecology and evolution. I also attended several very interesting presentations. Obviously there is a lot of focus on the human microbiome and the effect on health and disease. On Friday I attended a very interesting presentation by Eran Segal of the Weizmann Institute. His work showed that a lot of the differences in how people respond to nutrients is due to differences in the gut flora. So we are all different, but not because of our genes, but because of our microbiomes. This is why a general approach to nutrition (“cholesterol is bad”) doesnt work. He was able to make predictions about what constitutes a healthy diet for each individual. Fascinating! I always try to relate this surface water quality. Maybe the reason why our lakes often behave in unexpected ways is because of our general management approach (“phosphorus is bad”). Should we be thinking about “personalized diets” for each lake?</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.abstractsonline.com/pp8/#!/4358/presentation/1452">http://www.abstractsonline.com/pp8/#!/4358/presentation/1452</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.asm.org/index.php/asm-microbe-2017">http://www.asm.org/index.php/asm-microbe-2017</a></span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgs6oV7DvGN_s_1_QDXSCbIq2mGJPx2Jzp8qmWHlhU62Xh2nLzw8MSDX75x1HUyBwKIrnKETAjmcOWT5ECmBChbH1Rhl2LK-lGuKcZoC41tB8yMkmzrO7pKjdgN11GkzIh8G9GhX-kDS8cP/s1600/Time-magazine-cholesterol-covers.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" data-original-height="352" data-original-width="491" height="286" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgs6oV7DvGN_s_1_QDXSCbIq2mGJPx2Jzp8qmWHlhU62Xh2nLzw8MSDX75x1HUyBwKIrnKETAjmcOWT5ECmBChbH1Rhl2LK-lGuKcZoC41tB8yMkmzrO7pKjdgN11GkzIh8G9GhX-kDS8cP/s400/Time-magazine-cholesterol-covers.jpg" width="400" /></a></div>
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<a href="https://omegavia.com/" style="font-family: Arial, Helvetica, sans-serif;"><span style="font-size: x-small;">https://omegavia.com</span></a></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"> </span><a href="http://www.systemsbioecology.org/" style="font-family: Arial, Helvetica, sans-serif;">www.systemsbioecology.org</a><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com1tag:blogger.com,1999:blog-6315131785688544229.post-81634337978109905492017-05-19T02:46:00.000-07:002017-05-19T02:46:34.430-07:00Upcoming Talk: ASM Microbe 17 in New Orleans<span style="font-family: Arial, Helvetica, sans-serif;">If you are going to be in New Orleans for ASM Microbe 17, I hope to see you at my presentation:</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">"Individual-Based, Genome-Scale Modeling of Microbe Ecology & Evolution"</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">June 5, 2017, 11:00 - 11:30 AM</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;">Room 346</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;">Session 474 - Ecology of the Individual Microbe</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.abstractsonline.com/pp8/#!/4358/presentation/1452">http://www.abstractsonline.com/pp8/#!/4358/presentation/1452</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.asm.org/index.php/asm-microbe-2017">http://www.asm.org/index.php/asm-microbe-2017</a></span><br />
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<a href="http://www.systemsbioecology.org/" style="font-family: Arial, Helvetica, sans-serif;">www.systemsbioecology.org</a>Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-25591964858491369432017-03-29T05:59:00.003-07:002017-03-29T05:59:46.369-07:00Freeman Lecture: Lake Erie's Death, Resurrection, Re-Death, and the role of Models in Guiding a Re-Resurrection<span style="font-family: Arial, Helvetica, sans-serif;">I hope you will be able to join us for this year’s Freeman Lecture, which will be presented by Prof. Don Scavia of the University of Michigan. </span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.bsces.org/events/2017-john-r-freeman-lecture-496">http://www.bsces.org/events/2017-john-r-freeman-lecture-496</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://files.bsces.org/file/2017-Freeman-Flyer.pdf">http://files.bsces.org/file/2017-Freeman-Flyer.pdf</a></span><br />
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh7GuU0L9ZIWYnM0_I2hWBzEG0B0kTOl-jqZZ7ciMdAD1FcsQ14zPu0LCCAfEUpB1w1nIkw3g_upk2pPvgI3L_Eh596125ojfYtEC64uUDmiPubdBr0lPTLeCnT_5m5SUwsFlNLwIv5rUnS/s1600/Cyano.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><span style="font-family: Arial, Helvetica, sans-serif;"><img border="0" height="266" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh7GuU0L9ZIWYnM0_I2hWBzEG0B0kTOl-jqZZ7ciMdAD1FcsQ14zPu0LCCAfEUpB1w1nIkw3g_upk2pPvgI3L_Eh596125ojfYtEC64uUDmiPubdBr0lPTLeCnT_5m5SUwsFlNLwIv5rUnS/s400/Cyano.jpg" width="400" /></span></a></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><span style="font-size: x-small;">Picture:www.ibtimes.com</span></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.systemsbioecology.org/">www.systemsbioecology.org</a></span><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-74797445294811672432017-03-16T11:24:00.004-07:002017-03-16T11:24:37.239-07:00Neutral Biogeography of Lake Systems<span style="font-family: Arial, Helvetica, sans-serif;">I am pleased to announce the publication of Sahar Shirani’s paper “Neutral evolution and dispersal limitation produce biogeographic patterns in <i>Microcystis aeruginosa</i> populations of lake systems” in <i>Microbial Ecology</i>. </span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Compared to higher organisms, microbes have large population sizes and high dispersal rates. Consequently, their populations are often assumed to be well connected in space, and any spatial patterns are attributed to environmental differences. In this paper, we explore the role of dispersal limitation and neutral evolution in the biogeography of cyanobacteria in lake systems using an agent-based model (ABM) that simulates individual cells, including their transport, growth, death and mutation. Biogeographic patterns, quantified as nucleotide divergence and computed from the genomes of the model cells, can be substantial in some cases. These results contradict the common notion of no dispersal limitation for microbes, provide a benchmark for future biogeography studies and have implications for how lakes may respond to change.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">In this project, we used a novel modeling methodology. We simulate 20k individual cells, each with a full Microcystis genome, for up to 20k years. Then we analyze the evolved genomes from the model using BLAST and MAFFT/Bio-Phylo. Application of these bioinformatics tools to models is new and opens new concepts, like a dynamic phylogeny tree (see movie below) and this synergy with observations highlights the realism of the model</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Some interesting future applications of this model may include applying it to the human microbiome (see this paper <a href="http://science.sciencemag.org/content/326/5960/1694">http://science.sciencemag.org/content/326/5960/1694</a>) or bacterial dispersal by ship balast water (see this paper <a href="http://pubs.acs.org/doi/pdf/10.1021/acs.est.6b03108">http://pubs.acs.org/doi/pdf/10.1021/acs.est.6b03108</a>). The code is available at the link below and I am available to help and/or collaborate.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><span style="font-size: x-small;">Image source: NASA WorldView</span></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;">PAPER:</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://link.springer.com/article/10.1007/s00248-017-0963-5">https://link.springer.com/article/10.1007/s00248-017-0963-5</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">MOVIE: </span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://youtu.be/LV8th6TfALo">https://youtu.be/LV8th6TfALo</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">CODE:</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://github.com/fhellweger/LargeLakes">https://github.com/fhellweger/LargeLakes</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.systemsbioecology.org/">www.systemsbioecology.org</a></span><br />
<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-73422635250992705832017-03-16T10:11:00.000-07:002017-03-16T10:11:31.013-07:00Enough about simple!<span style="font-family: Arial, Helvetica, sans-serif;">One of the goals of my research program is to bring modern biology into the models we use to manage our waterbodies. When learning about the science in a certain area I am always impressed by how much we know about certain topics. On the other hand I feel that there is an obsession with finding simple solutions to complex systems, which limits the utility of biological research. In this blog post at “On Biology” I argue that biologists should be more like modern car mechanics and delegate understanding (not just number crunching) to computers.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Regular visitors to this blog may realize I am a bit on a crusade here. I have been writing papers criticising our community (of ecosystem modelers) with titles “100 Years since Streeter and Phelps: It Is Time To Update the Biology in Our Water Quality Models” and “75 years since Monod: it is time to increase the complexity of our predictive ecosystem models” and now “Biology 2.0: It is time to delegate understanding to computers”. And I am writing another one as we speak. I guess it is a phase I am going through...</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">BLOG POST LINK</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://blogs.biomedcentral.com/on-biology/2017/03/16/biology-2-0-it-is-time-to-delegate-understanding-to-computers/">http://blogs.biomedcentral.com/on-biology/2017/03/16/biology-2-0-it-is-time-to-delegate-understanding-to-computers/</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">SASM HOMEPAGE (hasn’t been updated for a while)</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.systemsbioecology.org/">www.systemsbioecology.org</a></span>Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-67092389557249968292017-02-09T05:00:00.001-08:002017-02-09T05:00:56.793-08:00New Position: Charles River Swimming Water Quality Monitoring and Assessment<span style="font-family: Arial, Helvetica, sans-serif;">We are looking for a graduate research assistant to do water quality sampling and analysis at a future swimming site on the Charles River <b><u><i>...STARTING MAY 1, 2017!</i></u></b></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Planning efforts are currently under way to open a permanent swimming location on the Charles River. A solid database of water quality observations is needed to support the management of the site. This position is for a Masters student to perform water quality monitoring and assessment. Specific tasks include sample collection and analysis for <i>E. coli</i> and total cyanobacteria cell counts in the laboratory, analysis and interpretation of the results, and summary and communication to stakeholders. Sampling and analysis will need to be performed on a daily basis during the swimming season (Memorial Day to Labor Day), with other times dedicated to data analysis and communication and coursework. This research project is a collaboration of the Charles River Conservancy (<a href="http://www.thecharles.org/">www.thecharles.org</a>) and Northeastern University (<a href="http://www.neu.edu/">www.neu.edu</a>). The dates of the position are May 1, 2017 through April 31, 2019. The student is expected to enroll in the Masters program at Northeastern University in the Department of Civil & Environmental Engineering or Marine & Environmental Sciences, advised by Prof. Ferdi Hellweger. The position provides a stipend, benefits and tuition. For more information see the Charles River Conservancy’s swimming site at <a href="http://www.thecharles.org/projects-and-programs/swim-park/">http://www.thecharles.org/projects-and-programs/swim-park/</a> or contact Ferdi Hellweger at ferdi@coe.neu.edu.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">This is an exciting project. We are looking for a student that is enthusiastic about the idea of swimming in the Charles River and a desire to do research in the urban environmental arena.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><span style="font-size: xx-small;">Image credit: Charles River Conservancy</span></span></div>
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-4940059971132984862017-02-04T02:44:00.000-08:002017-02-04T02:44:09.570-08:00IWA Dipcon 2017 in LA - Abstracts due March 1<span style="font-family: Arial, Helvetica, sans-serif;">We hope you will be able to join us for the <b>18th IWA International Conference on Diffuse Pollution & Eutrophication</b> held August 13-17, 2017 in Los Angeles. Abstracts are due March 1. Here is the website: </span><a href="http://www.iwadipcon2017.org/" style="font-family: Arial, Helvetica, sans-serif;">http://www.iwadipcon2017.org/</a><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-87856682146509967122017-01-06T02:02:00.001-08:002017-01-06T02:02:29.730-08:00THE THINGS WE THINK AND DO NOT SAY<span style="font-family: Arial, Helvetica, sans-serif;">I am pleased to announce the publication of “75 years since Monod: It is time to increase the complexity of our predictive ecosystem models”. This opinion paper contributes to the debate about the level of complexity in ecological modeling. I have been developing relatively complex models for some time now and often the complexity is the subject of criticism (as part of the Q&A part of talks and seminars and the journal and proposal peer review process). Over time I have come to develop counterarguments and I am now at a point where I feel it would be useful to share these with a larger audience. This paper is my attempt to deliver a broadside salvo at the critics of complex ecological models.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">A bit of a personal perspective: With this paper I am questioning some of the long-standing principles of ecological modeling, i.e. that models should be as simple as possible. Writing this paper made me think of the movie “Jerry McGuire”, where he writes an assay “The Things we Think but Do Not Say” criticising how things are done in his business. He ends up getting fired…</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Paper link:</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.sciencedirect.com/science/article/pii/S0304380016303209">http://www.sciencedirect.com/science/article/pii/S0304380016303209<o:p></o:p></a></span></div>
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-47786468996829404992016-12-17T12:37:00.004-08:002016-12-17T12:37:19.201-08:00Charles River Bathymetry Map Updated<span style="font-family: Arial, Helvetica, sans-serif;">There is a nice article in the Boston Globe about mapping the Charles River bathymetry. You can read it here:</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.bostonglobe.com/business/2016/12/16/charting-project-reveals-charles-river-depths/FMTKuYABfzHSLxggV0sXkK/story.html">http://www.bostonglobe.com/business/2016/12/16/charting-project-reveals-charles-river-depths/FMTKuYABfzHSLxggV0sXkK/story.html</a></span><br />
<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-25128032642806363802016-12-03T08:18:00.000-08:002016-12-03T08:18:02.982-08:00Ocean currents and temperature selection<div class="MsoNormal" style="text-align: justify;">
<span style="font-family: Arial, Helvetica, sans-serif;">I am pleased to announce our
latest paper on agent-based modeling of ocean microbes. Microbe biogeography
studies typically assume that the microbes are affected only by local
conditions. However, in areas with substantial advection (e.g. ocean currents),
upstream conditions may play a stronger role in shaping the local community.
Here we explore this effect for temperature selection in surface ocean
microbes. We develop a novel agent-based model and perform simulations to
quantify the effect of advection at the global scale. Our results show that
advection by currents can change the effective selection temperature of
microbes by several degrees Celsius, and therefore should be considered in
microbe biogeography studies. We then apply our results to three global
datasets and for all we can better explain observations when currents are considered.
We make our results accessible to the broader community by providing an atlas
of temperature corrections.<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;">I think this is an interesting
study with some important conclusions. In terms of my research program, this
model also represents a stepping stone for a more complex global microbe
agent-based model. Specifically, we are now working on integrating a gene-level
model of <i>Synechococcus </i>I developed previously (see link below) into this model.
We will then make predictions of gene, transcript and protein levels at the
global scale. Pretty exciting!<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;">PAPER<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167010">http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167010</a><o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;">YOUTUBE MOVIE<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://youtu.be/CGvGNskYgTU">https://youtu.be/CGvGNskYgTU</a><o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;">CODE AT GITHUB<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://github.com/fhellweger/GlobalTemp">https://github.com/fhellweger/GlobalTemp</a><o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;">SYNCHOCOCCUS MODEL PAPER<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.sciencedirect.com/science/article/pii/S0304380010001602">http://www.sciencedirect.com/science/article/pii/S0304380010001602</a><o:p></o:p></span></div>
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-23374123305980472642016-08-23T07:21:00.000-07:002016-08-23T07:21:21.267-07:00ISME Conference Report<span style="font-family: Arial, Helvetica, sans-serif;">I am in Montreal at ISME16 (16th International Symposium on Microbial Ecology). Yesterday I presented a poster on our <i>Anabaena </i>- nitrogen interaction model. This is a very exciting meeting with many presentations that are very close to my research area. I listened to talks about the role of uncultured bacteria that live in symbiosis with eukaryotes and fix N in the ocean and “cable bacteria" that move electrons over distances of centimeters in sediments. There are so many interesting ecological problems where our modeling approach can make a contribution. The list of “future projects” continues to grow... </span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.isme-microbes.org/isme16">http://www.isme-microbes.org/isme16</a></span>Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-60292529421492836212016-08-17T09:48:00.000-07:002016-08-17T09:48:26.196-07:00Special Issue in Frontiers in Microbiology<span style="font-family: Arial, Helvetica, sans-serif;">In collaboration with Frontiers in Microbiology, section Systems Microbiology, we are organizing a Research Topic titled "The Individual Microbe: Single-Cell Analysis and Agent-Based Modelling", hosted by Weiwen Zhang, Johan Leveau, Clara Prats, Jan-Ulrich Kreft, Ferdi L Hellweger. We would like to encourage you to contribute to this topic. Please find more information at the homepage we have created on the Frontiers website, which defines the focus of the topic, and where all published articles will appear.</span><br />
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<a href="http://frontiersin.org/Systems_Microbiology/researchtopics/The_Individual_Microbe_Single-Cell_Analysis_and_Agent-Based_Modelling/5193"><span style="font-family: Arial, Helvetica, sans-serif;">http://frontiersin.org/Systems_Microbiology/researchtopics/The_Individual_Microbe_Single-Cell_Analysis_and_Agent-Based_Modelling/5193</span></a><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Please note the submission deadline for this Research Topic: Apr 30, 2017</span><br />
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<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-7539400170466391722016-07-13T10:41:00.002-07:002016-07-13T10:41:20.843-07:00SIAM Conference Report<span style="font-family: "arial" , "helvetica" , sans-serif;">I am at the SIAM (Society of Industrial and Applied Mathematics) Life Sciences conference here in Boston. This morning I made a presentation about our <i>Anabaena </i>model and listened to many interesting talks about modeling microbes.</span><br />
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Here is a link to the program and abstract:</span><br />
<span style="font-family: "arial" , "helvetica" , sans-serif;"><a href="http://www.siam.org/meetings/ls16/">http://www.siam.org/meetings/ls16/</a></span><br />
<span style="font-family: "arial" , "helvetica" , sans-serif;"><a href="http://meetings.siam.org/sess/dsp_talk.cfm?p=78264">http://meetings.siam.org/sess/dsp_talk.cfm?p=78264</a></span><br />
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<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-78782472325258149392016-06-27T13:13:00.002-07:002016-06-27T13:13:22.737-07:00Gordon Research Conference Report<span style="font-family: "arial" , "helvetica" , sans-serif;">I am at the Gordon Research Conference on Environmental Sciences - Water in New Hampshire. Today I gave a talk about our research. In some ways this conference marks a 10 year anniversary for me. In 2006 I was here and presented my first poster on agent-based modeling (ABM) of phytoplankton. That was a real milestone, because since then this has been the defining theme of my research. In fact, that poster is still prominently displayed in my office :) </span><br />
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<span style="font-family: "arial" , "helvetica" , sans-serif;">A main goal of my presentation was to start a discussion about updating the biology in our water quality models. One reason for doing this is to bring models up to the level of modern observations (see figure below). When we first developed water quality models in the 1970s, people were measuring total phosphorus and chlorophyll <i>a</i>, and those were adopted as state variables in our model. Since then, observations have evolved and now observations include DNA, RNA, etc. However, our models have not kept up. This disconnect really limits the utility of our models, and I think it is leading to the extinction of a specialty: water quality modelers. A big problem, because most of our waterbodies are polluted and models are important tools for management and research in this area :(</span><br />
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<span style="font-family: "arial" , "helvetica" , sans-serif;">Here is a link to the program:</span><br />
<span style="font-family: "arial" , "helvetica" , sans-serif;"><a href="https://www.grc.org/programs.aspx?id=11255">https://www.grc.org/programs.aspx?id=11255</a></span><br />
<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-10098502597039991842016-06-09T14:51:00.000-07:002016-06-09T14:51:21.627-07:00IAGLR Conference Report<span style="font-family: Arial, Helvetica, sans-serif;">I am in beautiful Guelph, Ontario, Canada for IAGLR's 59th annual Conference on Great Lakes Research. I was not planning on coming here, but my graduate student, Sahar Shirani, was not able to get a visa, so here I am. Today I presented Sahar’s research on the role of neutral evolution and dispersal limitation in the biogeography of <i>Microcystis</i> in the Great Lakes. Here are links to our abstract and the conference:</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://iaglr.org/conference/abstracts/pub_abstract_view.php?abstract_id=1454097536">http://iaglr.org/conference/abstracts/pub_abstract_view.php?abstract_id=1454097536</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://iaglr.org/iaglr2016/">http://iaglr.org/iaglr2016/</a></span><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-51836811330878405652016-06-06T06:14:00.000-07:002016-06-06T06:14:01.001-07:00The journey continues: NRM paper is out<span style="font-family: Arial, Helvetica, sans-serif;">I am glad to announce that our latest review/opinion paper on agent-based modeling for microbes, written under the leadership of Jan Kreft, is now out in Nature Reviews Microbiology. This is the latest installment of “ABM for microbes” review papers, a journey that now spans almost a decade from Hellweger (2007) to Hellweger and Bucci (2009) to Kreft et al (2013) and now Hellweger et al (2016). Judging from the Impact Factor of the journals these papers were published in, the importance of this subject is increasingly being recognized (see figure below). If you are still using concepts from chemistry to model biology or ecology - STOP. Join the revolution!</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Hellweger et al. (2016)</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.nature.com/nrmicro/journal/vaop/ncurrent/full/nrmicro.2016.62.html">http://www.nature.com/nrmicro/journal/vaop/ncurrent/full/nrmicro.2016.62.html</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Kreft et al. (2013)</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.pnas.org/content/110/45/18027.short">http://www.pnas.org/content/110/45/18027.short</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Hellweger and Bucci (2009)</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.sciencedirect.com/science/article/pii/S0304380008004390">http://www.sciencedirect.com/science/article/pii/S0304380008004390</a></span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Hellweger (2007)</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.ingentaconnect.com/content/wef/wefproc/2007/00002007/00000012/art00001">http://www.ingentaconnect.com/content/wef/wefproc/2007/00002007/00000012/art00001</a></span><br />
<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-82840189724163718492016-05-16T07:52:00.001-07:002016-05-16T07:52:14.514-07:00Capstone Group Wins NEWEA Design Competition<div class="MsoNormal">
<span style="font-family: Arial, Helvetica, sans-serif;">Congratulations to Alston Potts, Greg Coyle, Andrew Gillen
and Meghan Bruckman, and their mentor Annalisa Onnis-Hayden, for winning the New
England Water Environment Association (NEWEA) student design competition. Their
project “Restoring the cycle: Northeastern University On-site Wastewater
Reclamation and Reuse” combined the design, construction and operation of a wastewater
treatment pilot plant, as well as a web site – all in one semester! You can
read more about these news here:<o:p></o:p></span></div>
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<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://www.civ.neu.edu/news/capstone-team-wins-newea-student-design-competition">http://www.civ.neu.edu/news/capstone-team-wins-newea-student-design-competition</a><o:p></o:p></span></div>
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-89009666928082620352016-04-28T11:28:00.000-07:002016-04-28T11:28:05.577-07:00Anabaena Paper Published<div class="MsoNormalCxSpFirst">
<span style="font-family: "Arial",sans-serif;">I am pleased to report that the <i>Anabaena</i> model paper is now
published in Environmental Microbiology. <o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;">In this paper we present a dynamic, mechanistic, gene level
model of <i>Anabaena</i> – nitrogen interaction. This model is unique and constitutes
a significant step in the area of microbial ecology, where models are typically
based on concepts developed over 50 years ago (i.e., Monod kinetics), do not
include modern biology and do not make predictions commensurate with modern
observational technologies (e.g., transcript levels). The model development
process is also novel in the context of microbial ecology. It builds on a large
database of empirical observations, data from 55 papers (269 experiments) were
digitized and used for model-data comparison (i.e. a meta-analysis). The model
helps to interpret the observations. For example, application to isotope
tracing experiments suggests a role for an N storage pool, consistent with
recent observations. We use the model to explore an important question about
the efficacy of reducing nitrogen to control lake eutrophication. Beyond these
results we propose that our approach constitutes a way to summarize
observations that has significant advantages over the traditional review paper
when the amount of observations is large. We believe this paper makes a
significant contribution to the biology and ecology of <i>Anabaena</i> and presents a
novel approach that is of interest to researchers in other areas of
microbiology and ecology.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;">I want to use this post to lay out some of the thoughts I
have about possible follow-on projects for this model. The overall “master
plan” for the <i>Anabaena</i> model is shown in the figure below, and some more
details follow. Please contact me, if you are interested in collaborating on
any of these projects.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Anabaena</i> Lab: This is done now. To give you some idea of
the effort involved: The <i>Anabaena</i> Lab model took much of my time over the
course of a year. I think on average about 4h/day.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Anabaena</i> Lab Validation: This is a validation exercise. It
would involve taking additional papers that were not used in the model
development and comparing the model to those. The present model was developed
and compared to experiments from 55 papers. This exercise may include about 10
papers. I already have these papers identified. This would be a good MS thesis project for a student. Along with this paper, I would like to publish
the source code and user guide of the model as well.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Anabaena</i> Field: The present model can be applied to a real
lake. Since it only includes <i>Anabaena</i>, this lake would have to be dominated by
<i>Anabaena</i>. If everything goes smoothly, this could also be a good MS thesis project.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Microcystis</i> Toxin Lab: This would involve taking the
present model and adapting it to <i>Microcystis</i>. The basic structure would be the
same, except that <i>Microcystis</i> does not fix N. This is easily handled in the
model by “knocking out” <i>nifH</i> and associated genes. Then the model would need to
be calibrated to observations of <i>Microcystis</i>. Then, the toxin production genes
and pathways would have to be programmed and calibrated/validated. This will
require more work, comparable to the <i>Anabaena</i> Lab project, and a good PhD thesis topic.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Anabaena</i> Energy Lab: The present model does not explicitly
track intracellular energy (i.e. in terms of ATP or equivalent) and tie it to
growth. For example, the cost of fixing one N2 vs. taking up and reducing one
NO3 is not explicitly considered in the model. I could, for example, simply
increase the NifH rate and then the cells would grow faster on N2 than NO3.
This change would make the model more mechanistically detailed and correct.
This will require more work, comparable to the <i>Anabaena</i> Lab project, again a good PhD topic.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Microcystis</i> Field: Once the <i>Microcystis</i> model is coded we
could apply it to a real lake. Again, this would require that the lake is
dominated by <i>Microcystis</i>. Of course, it is unlikely that we would find such a
system anywhere [this is a Taihu insider joke].<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Anabaena</i>/<i>Microcystis</i> Lab Competition: This came out of some
discussion and ideas we had about light energy and competition between these
species.<o:p></o:p></span></div>
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<span style="font-family: "Arial",sans-serif;"><i>Anabaena</i>/<i>Microcystis</i> Competition Field: Finally, the whole
model can be used to explore the competition between these two species in the
field.<o:p></o:p></span></div>
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<span style="font-family: Arial, sans-serif;">Link to the paper:</span></div>
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<span style="font-family: Arial, sans-serif;"><a href="http://onlinelibrary.wiley.com/doi/10.1111/1462-2920.13299/full">http://onlinelibrary.wiley.com/doi/10.1111/1462-2920.13299/full</a></span></div>
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<span style="font-family: "Arial",sans-serif;">Link to the YouTUBE movie:<o:p></o:p></span></div>
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<span style="font-family: Arial, sans-serif;"><a href="https://youtu.be/ha6Wq2U-hWk">https://youtu.be/ha6Wq2U-hWk</a></span></div>
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-90224490062380791152016-04-15T13:17:00.001-07:002016-04-15T13:17:52.636-07:00Environmental Capstones<span style="font-family: Arial, Helvetica, sans-serif;">It’s that time of year again... Capstones! Please join us for the 2016 Environmental Capstone student presentations. This year, we have a variety of interesting projects, including designing refugee camps in Haiti and Greece, a floodwall to protect the Logan Airport power station from hurricanes, a water management system at the Blue Hills Ski Area, a dam on the Charles River, an off-the-grid home, a solar system for an industrial client, a food waste composting system for the Town of Melrose and a wastewater treatment plant for the Northeastern University campus. Nine Capstone teams have been working hard all semester and now it’s time to see what they came up with. Please join us! A flyer with more details is posted here: </span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://dl.dropboxusercontent.com/u/58018213/EnvCapstone2016s.pdf">https://dl.dropboxusercontent.com/u/58018213/EnvCapstone2016s.pdf</a></span><br />
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Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-25172871594630757532016-04-05T07:08:00.000-07:002016-04-05T07:08:19.363-07:00Freeman Lecture<span style="font-family: Arial, Helvetica, sans-serif;">Please join us for the annual John R Freeman Lecture, which will be held at Northeastern this year. This year’s speaker will be Prof. John H Lienhard V from MIT and he will be talking about desalination. The problem of freshwater availability is growing with the increase in population across the globe, and desalination is one important solution. The event will be on April 11 in room 20 WVF. It starts with a reception (free food) at 6pm and then the lecture at 7pm.</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://web.mit.edu/freeman-bsces/index.html">http://web.mit.edu/freeman-bsces/index.html</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="http://web.mit.edu/freeman-bsces/2016%20John%20R%20Freeman%20Flyer.pdf">http://web.mit.edu/freeman-bsces/2016%20John%20R%20Freeman%20Flyer.pdf</a></span><br />
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<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0tag:blogger.com,1999:blog-6315131785688544229.post-24110213836240775072016-03-20T12:42:00.000-07:002016-03-20T12:42:03.719-07:00@ASM Conference Report<span style="font-family: Arial, Helvetica, sans-serif;">I am at DCA on my way back to Boston. We just finished a conference on single-cell analyses and agent-based modeling at the ASM headquarters in Washington DC. This is an excellent venue. It was great to be among so many like-minded people and I really enjoyed the presentations and discussions. Here are the slides from my opening remarks and presentation and a copy of the program.</span><br />
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<span style="font-family: Arial, Helvetica, sans-serif;">Intro Slides</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://www.dropbox.com/s/3gg5t3fuyzd4hud/atASM_ConferenceIntroduction.pptx?dl=0">https://www.dropbox.com/s/3gg5t3fuyzd4hud/atASM_ConferenceIntroduction.pptx?dl=0</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;">Anabaena Slides</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://www.dropbox.com/s/i6x0vhjryo7rng3/atASM_AnabaenaNitrogen.pptx?dl=0">https://www.dropbox.com/s/i6x0vhjryo7rng3/atASM_AnabaenaNitrogen.pptx?dl=0</a></span><br />
<span style="font-family: Arial, Helvetica, sans-serif;">Conference Program</span><br />
<span style="font-family: Arial, Helvetica, sans-serif;"><a href="https://www.dropbox.com/s/p2sis3yl4our2f4/atASM%20Conf%20Program.pdf?dl=0">https://www.dropbox.com/s/p2sis3yl4our2f4/atASM%20Conf%20Program.pdf?dl=0</a></span><br />
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<br />Ferdi Hellwegerhttp://www.blogger.com/profile/14588169901530129379noreply@blogger.com0